Nitrofurantoine

Nitrofurantoine – 100 mg Tablets

Nitrofurantoin is an antibacterial, which belongs to the group of nitrofuranes.
The mechanism of action of nitrofurantoin has not yet been clarified. There is evidence that this substance inhibits a range of enzymatic systems of bacteria and confirmed that it interferes in the early stages of bacterial carbohydrate metabolism, by inhibiting acetyl coenzime A. Nitrofurantoin acts against a broad spectrum of common pathogen microbes of urinary tract. Most strains of Escherichia coli are sensitive; also, most of strains of Klebsiella – Enterobacter are sensitive to nitrofurantoin.

Nitrofurantoine is indicated in prophylaxis and treatment of acute or recurrent, uncomplicated lower urinary tract infections, either spontaneous or following surgical procedures. Nitrofurantoine is specifically indicated for the treatment of infections when due to susceptible strains of Escherichia coli, Enterococci, Staphylococci, Citrobacter, Klebsiella and Enterobacter. Most strains of Proteus and Serratia are resistant. All Pseudomonas strains are resistant.