Nitrosorbit contains the active substance isosorbide dinitrate. The basic pharmacological effect of isosorbide dinitrate, as all organic nitrates, is relaxing vascular smooth muscles as a result of intracellular cyclic guanosine monophosphate production inducement. Arterioles relaxation reduces systemic vascular resistance and blood pressure.
Nitrosorbit 10 mg tablets are indicated in:
• prophylaxis and treatment of angina pectoris;
• left ventricular failure.