Aspirine is a salicylic nonsteroidal anti-inflammatory drug (NSAID) which shares many common characteristics with other NSAIDs. Aspirine has analgesic, antipyretic, anti-inflammatory and antirheumatic effects. Aspirine lowers body temperature by dilating peripheral blood vessels. It has anti-inflammatory and analgesic effects through inhibition of prostaglandin synthase enzyme complex. By acetylating platelet cyclooxygenase, Aspirine inhibits synthesis of thromboxane A2, a prostaglandin derivative and potent vasoconstrictor that stimulates platelet aggregation and release. Aspirine inhibits platelet aggregation.
Aspirine 500 mg tablets are indicated in:
• pain of mild or moderate intensity such as headache, dental pain, neuralgia, myalgia, menstrual pain, postraumatic pain, postoperative pain;
• febrile patients to lower body temperature;
• inflammatory diseases such as rheumatic fever, rheumatoid arthritis, and osteoarthritis.