Kardiospir contains acetylsalicylic acid as active substance. Acetylsalicylic acid (aspirin) is a nonsteroidal anti-inflammatory drug (NSAID) of the salicylate group and shares many common characteristics with other NSAIDs. It has analgesic, antipyretic, anti-inflammatory and antirheumatic effects. Acetylsalicylic acid lowers the body high temperature by dilating peripheral blood vessels. It exerts anti-inflammatory and analgesic effects through inhibition of prostaglandin-synthetase enzyme complex. By acetylating platelet cyclooxygenase, acetylsalicylic acid inhibits the synthesis of thromboxane A2, a prostaglandin derivative and potent vasoconstrictor that stimulates platelet aggregation and their release. Acetylsalicylic acid inhibits platelet aggregation.
It is indicated in:
• prophylaxis of cerebrovascular diseases or myocardial infarction (due to its antiplatelet effect);
• unstable angina (a special, dangerous type of coronary heart disease associated with chest pain even when at rest);
• minor strokes in the brain (cerebral ischemic strokes including transient ischemic attacks).