Meliozol ovules contain the active substance metronidazole. Metronidazole, a synthetic derivative of nitroimidazole, acts against gram-positive and gram-negative anaerobic microorganisms (Bacteroides species, including the B.fragilis bacterial group, Clostridium species, Eubacterium species, Peptococcus species, Peptostreptococcus species and against protozoan (Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia). The mechanism of action of metronidazole is not yet clear. It is thought that metronidazole inhibits the synthesis of DNA. It has bactericidal action.
Meliozol ovules are used in:
• female urogenital trichomoniasis (Trichomonas vaginalis);
• bacterial vaginosis (also known as non-specific vaginitis, anaerobic vaginosis or Gardnerella vaginitis).