Prednizon

Prednizon – 5 mg Tablets

Prednisone is a glucocorticoid that inhibits the formation, releasing and activity of endogen inflammatory mediators, including prostaglandins, kinins, histamin, liposomal enzimes and complement cascade. It also alters the organism immune response. In haematopoetic system it decreases lymphocytes, eosinophils and basophils number, but increases neutrophils, thrombocytes and erythrocytes. Prednisone antagonises the vitamin D effect in calcium absorption from the digestive apparatus (osteoporosis manifestation) and it stimulates hydrochloric acid release. In central nervous system it acts as a promoter, by causing euphoria, psychosis and convulsions.

Prednizon is indicated in: bronchial asthma; rheumatic arthritis; systemic lupus erythematosus; dermatomyositis; collagen diseases (except systemic sclerosis); poliarteritis nodosa; skin diseases, including pemphigus bulosus and pyoderma gangrenosum; acute interstitial nephritis; ulcerative colitis; Crohn’s disease; sarcoidosis; rheumatic carditis; haemolytic anemia (autoimmune); acute lymphoid leukemias, malignant lymphoma; multiple myeloma, idiopathic thrombocytopenic purpura; immunosuppressant etc.